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In this video you’ll discover the nootropics benefits of Nicotine. Including why we use Nicotine as a nootropic, recommended dosage, side effects and clinical research.

Nicotine is an alkaloid most famously found in tobacco leaves. But nicotine is also present in very small amounts in plants from the Solanaceae or nightshade family including potatoes, tomatoes and eggplant.

Nicotine has been used by humans for its psychoactive (nootropic) properties for thousands of years.

Nicotine works primarily by upregulating nicotinic acetylcholine receptors (nAChR) in the brain. Boosting the release of acetylcholine (ACh), dopamine, serotonin, and glutamate. Affecting alertness, attention, cognition, memory and mood.

Nicotine modulates the connectivity and structure of brain networks. And improves whole-brain communication efficiency. Boosting overall cognitive and brain function.

Since we’re investigating nicotine as a nootropic here, it’s important to point out that I am not encouraging smoking. Smoking tobacco has been shown to increase cognition.

But the harmful effects of tobacco have been proven extensively. Including a study that showed life-time smokers have less gray matter in the prefrontal cortex compared to non-smokers. Affecting the brain’s reward, impulse control and decision-making circuits.

Nicotine as a nootropic is dosed at 1 – 2 mg on an as needed basis. Nicotine gum typically comes in 2 – 4 mg. You can cut a 4 mg piece of gum in half for a 2 mg dose. Gum releases the nicotine dose over the course of 20 – 30 minutes. The problem with nicotine gum is aspartame along with other unhealthy sweeteners.

My preferred method is nicotine lozenges. The mini-lozenges are best because they’re not full of toxic chemicals like the larger lozenges. The 2 mg mini-lozenge cut in half provides a nice cognitive boost in 10 – 20 minutes.

Studies have shown that upregulation of nAChR is dose dependent. And too much nicotine desensitizes these receptors. So low doses of nicotine are key in using nicotine as a nootropic for cognitive benefit.

This indepth Nicotine review covers:

00:23 Nicotine as a nootropic
03:53 How does Nicotine work in the brain?
06:07 Nicotine benefits
07:23 How does Nicotine feel?
08:17 Nicotine clinical studies
09:27 Nicotine recommended dosage
10:32 Nicotine side effects
11:18 Types of Nicotine to use as a nootropic

For more on Nicotine including a full transcript of this video and links to clinical studies, go to:

For a full list of all the popular nootropics used today, go to:

I upload new videos every week providing individual nootropic reviews, and tips on the best nootropic stacks no matter what your brain optimization goals. For a list of all the videos I have so far, go to my channel:


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