The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab)

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In a creative stroke inspired by Hollywood wizardry, scientists from the Kishony Lab at HMS and Technion ( have designed a simple way to observe how bacteria move as they become impervious to drugs. The experiments are thought to provide the first large-scale glimpse of the maneuvers of bacteria as they encounter increasingly higher doses of antibiotics and adapt to survive—and thrive—in them.

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ophello says:

Welp…..were fucked.

Clorox Bleach says:

Now Im scared

VisenX says:

Follow your prescriptions to avoid this.

musicwelikemang says:

Amazing video. This should be shown to every person studying medicine and every qualified current doctor.
The rate of bacterial evolution is not well understood in the GP community and they continue to over prescribe antibiotics for non-issues and even viruses.

John Carboni says:

the strong bacteria survive & pass their traits to their offspring, that is NOT evolution.even humans pass stronger traits to their offspring, built in survival tactics by the awesome Creator .

david franco says:

Forgive me for my lack of knowledge on this topic. I am wondering if the mutant colony, at the 1,000 level of antibiotics, spread just as easily as the colonies in the agar with no antibiotics if the sample is placed in the 0x section along with other bacteria? Will that mutated colony, now at the 0x level, spread at the same rate as the other colonies at 0x? Has the mutant colony inherited the ability to withstand the 1x, 10x, 100x, and 1,000x level of antibiotics and spread as if all levels resembled the 0x level of antibiotics? If you take a sample of the mutated colony and start the sample at 0x antibiotics and run the same experiment, will that colony mutate again in a stairstep pattern of growth/mutation or will it be a fluid and linear spread because it is written in its DNA? I guess what I'm trying to ask is after 7-8 generations of mutations is there enough change in the DNA, from the DNA of the original colony, that the 1x and 10x will be as effective as it did on the 2nd and 3rd generations? Forgive me if the answer to this question obvious.

Jerry Overcast says:

Aanndd no one sees the irony of breeding a super bacteria to prove there is such a thing?

soldatheero says:

evolution in action, but not evolution by natural selection and random mutations. Intelligent mutations, not random.. we need to figure out the cause of that intelligent ability to mutate because it is clearly not random.

QuantumFrost says:

Creationists aren't denying mutations
It's the actual analysis of mutations that don't go against their view. A degenerative change can be beneficial and cause an antibiotic resistance

ElectronicaJohnnyK says:

please do show this to anyone that doubt Evolutionary theory.

Krehlmar says:

Harvard using "feet"… Godamnit get your shit together

Akuma says:

How terrifying…….. educational… but terrifying

Braden Jones says:

That’s not evolution that’s natural selection. You are selecting for resistance to antibiotics. Cmon Harvard. You should well know how this works with the bacterial shell containing enzymes to break down the antibiotic. This is selection from a population already containing a group resistant to this antibiotic. You will find that the bacteria that survived in the 1000x antibiotic will be outcompeted by the original in the non bacterial aggregate

Cry Whit says:

Does antibiotic lose its strength when it sits out like that?

Егор Молот says:

нам всем пиздец

Jonathan Gasser says:

I wasn't expecting the bacteria to be "popping" into higher concentration areas. But it makes sense, you only need one lone mutation, somewhere, out of the millions of dead – and it spreads.

Piotrek K says:

So, if bacteria can evolve to be antibiotic resistant in such short period of time, how is it possible that antibiotics still have some impact on them? Shouldn't they evolve shortly after humans stated to use antibiotics?

nick l says:

That looks a lot like humans on a radioactive planet

Larry Douglas says:

At what point will they become anything but a bacteria? I understand adaptation and the experiment here trying to show evolution but i have a difficult time combining the two ideas into one. Anyone have a link or video to explain this better?

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